yeah, you can run a newer vortec motor in your truck, no problem..
you just need the big ol' $$$ intake that gmpp makes, or you could use a carberated intake and use an adapter (although i really dont recommend that)
check out this web site
http://thirdgen.org/techbb2/forumdis...?s=&forumid=17
that link should take ya to there "tbi tech board", its for third generation camaro's, but the same concept applys
good luck man!