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I know there's been a lot of talk about using an Expedition IRS and inquiries about the pros and cons. I also know there's been at least one 67-72 that's had a custom chassis built with an Expedition IRS out back (pretty sure it's an editor of Sport Truck's project?)

Anyways, I just got done installing one in a 50 Merc. Not quite a truck, but the IRS would definitely cross over nicely. Pretty much all anybody would want to keep would be the center section, the axles, the hubs, and the brakes. I don't think the rest of the components would be easily incorporated.

I went ahead and did some fabricted control arms, and spindles this time around, but will deinitely do tubular arms on the next one. The axles will have to be narrowed for this application, but they should work nicely on a C10. The differential on this thing is HUGE... I am sure it could handle a ton of torque. It's not the prettiest thing, but for the money I think it's a good IRS candidate.

here's some pics of the merc. chassis...