The 292 has a tab with two tapped bolt holes on each side of the front of the block.
You could design and build a horseshoe style mount that would bolt to a stock front motor mount or run a pair of mounts down and use something like the 55/57 biscuit mounts. It's going to take some designing and fabricating but it can be done. I'd probably want to use some stiff cardboard to mock up the first design and after it looks right transfer it to steel.
You can see that the right side tab located just in front of the oil filter makes it easy to setup an engine mount that fastens to the stock front crossmember.
If he is running a Chev 3 or 4 speed trans he can run one of the V8 truck bellhousings that has the mounts. One like this
http://cgi.ebay.com/ebaymotors/63-64...Q5fAccessories is what I have in my 48 and they aren't all that hard to find. That will allow him to run the stock rear engine mounts and locate the engine where it needs to be. He will probably have to run the clutch fork that fits and works the best in the truck.
Here is the 250 connected to the truck bellhousing. the 292 will be about 1-1/2 inches taller.
I'm not sure about waterpump clearance. The 292 pump is about 5 inches long out to the end of the shaft from the block.
I think I had to shorten the pump on my 250 when I put it in my truck but it came out of a 74 Pointiac Ventura, I don't have the right radiator in my truck to be able to go out an figure clearances.
I also used a short pulley to make it work.
This is the first time I have ever shown photos of my engine compartment as it sits. 100,000+ miles with the 250 that had 92K on it when I installed it in 1989. Things are a bit nasty but it served as my daily driver and work car during most of that time.