the 307 should handle that just fine. you will probably get ~15 mpg if you really keep your foot out of it, but both of these depend on axle gearing too. If its 3.08 you will have a harder time towing but will get better mpg unloaded, etc.
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1969 GMC K2500 
1996 Honda Accord
2007 Kawasaki KLR 650
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