Heater core and cover are different (outlets are in a different position to clear the valve cover).
Big-block Novas also used a different transmission crossmember, since the motor mounts offset the motor toward the passenger side. The BBC automatics were all Turbo 400's, & they use a tubular mount that mounts the tranny support farther to the rear. The BBC stick-shift crossmembers resemble the one you probably have, but again the mount holes are offset to the right. Here's a 1st-gen Camaro (same underneath as a '72 Nova) thread that says you can redrill the standard crossmember:
http://www.camaros.net/forum/ultimat...=003396#000000
http://www.camaros.org/trans.shtml#Crossmembers
http://www.chevynova.org/BigBock.html has some motor mount pics.