Rubber Seals around my Window

[Hair]

I have those big black rubber seals around my front and rear windows. I was wanting to know. Can I remove those and replace them without taking out the glass? I see that some trucks have the chrome molding around the windows. I like that better. Could I buy the chrome molding and swap it out? Is that doable. I'm sanding the truck down to paint right now, and instead of masking the rubber and having little bitty spots of a different color that you can always see under there, I was wanting to just pull the seals out and tape up the glass and paint it and then stick the rubber back in. Is this done pretty easily or is it a big hassle to mess with? How would I go about removing the rubber seals? If I removed the seals and worked on the truck for a few months would the glass move on me and make it hard to get the seals back in? If I have to take the whole glass out, forget it, I'll just mask it. What am I dealing with here?