manifold & carb swap sb350, need info

[dukcaln]

so I am pretty sure I have some carb issues with the original q-jet. I have a howards roller cam, bored .30 over, headers, balanced and still run the stock 1972 manifold and q-carb. I have available to me a really nice manifold and carb set up and want to make the swap soon. I want to put on a Weiand x-celerator manifold and Edelbrock performer 1406 (600cfm) carb..... will I gain or loose anything. I think the manifold swap will be good for the performance and I was wondering will the carb work good. benefits disadvantages, please post your thoughts.......