windshield rust

[grizz]

I found some rust behind the windshield weather stripping on the inside of the cab along the roof. The rust seem to be only in the middle of the windshield. If I was to take the windshield out, would I be able to replace it to clean the rust. Would I have problems getting the seal back in? I've been told that this is a place that they rust out and I am afraid to that would do more damage than good. Is there anything that can be done to replace the edge if it is real bad.