Late model frame swap

[250cows]

I have a 66 swb fleetside, putting in a 5.3 w/ 4L60E. I thought why not change to late model 2wd frame(99-06) while i am at it, which would have 6 lugs and front and rear disk brakes. Has anyone done this or seen it done. Or is it easier to change front suspension and rear axle. Any warnings or odd-ball looks that might discourage me would be appreciated, ie. would the frame rails be to low under cab and front of bed? width of rear axle, and front suspension? I have changed 47-53 models to lwb s10 , so I can handle the work, just dont want a turd in the punch bowl look .