No spark on cylinder NO. 2??

[1972GMCsierra4x4]

So ever since I put a newer motor in my truck it's been a turd. I know that stock 350s are huge powerhouses, but it was bad enough I needed to check it out. So I pulled my plugs and saw that my number two cylinder was fouled up and wet. Voila, I found the right cylinder. I didn't have the tools to check compression so I tested for spark first and there isn't one. What could be causing this? I'm asking because I am running a Pertronix Ignitor II distributor, and I don't have much experience with them. I know all my wires, plugs and coil are good. Does anyone have thoughts on what could be the problem within the distributor?