Electrician on board ?

[FAKKY]

Going to run a subpanel from my house toa new garage for my truck hobby workshop.
Pulling permit myself.

1st thing Im a little stuck on. Original thought was ....

240 - 50A.
6/3 NMB wire for 75ft through crawlspace.
Then 2224 mhf wire in conduit to subpanel underground with schedule 40 UL 175ft away.

Spliced with port multitap connector.

But - I cant quite work out if 6/3 combination with 2224 is ok over this distance - seems ok on some voltage drop calcs to remain under 3% and not ok barely on others. Big step up in $$ 2x to 4/3.

Can you use 2224 all the way ? or some other aluminum cable like SER of higher amperage/capacity.
I dont see many people do that in threads though.

thx