Driver's door lock issue...

[alsriv2]

I did not want to steal another person's thread (IntegratedTJ) but I have a similar problem with my '69 C10. Older resto, great door gaskets...both passenger and drivers door shut great without binding.
Driver door key lock works smooth and locks the door fine with no binding when the door is open.
Close the door, Key will not fully turn to the lock position. It will start the move of the rod but will stop midway and not allow me to lock the door. Passenger door works fine.
Also with drivers door closed, cannot manually lock the door from inside either.

Any help or suggestions would be appreciated.