Offset center section

Hey guys this is kind of a continuation from one of my posts in the 47-59 forum. http://67-72chevytrucks.com/vboard/s...86#post2612586

My question is concerning a 8.8 rear end i would like to use in my 53 1/2 ton, the exploder rear end is 59 3/4" wide but a offset pinon of 2 3/16 inches will this cause drive shaft vibration?