Changing locks on Subruban?

[Kudzupatch]

Avid outdoors person here and lost an item from my Suburban that had a spare set of keys in it. Not sure if it was stolen of left behind, either way I am concerned about those keys being out in the wild and someone knowing they keys are to my vehicle.

So what is involved in changing door locks out? I had to replace the ignition switch so I am familiar with that. I would think doors are straight forward but I have never taken one apart.